The award, which includes $50,000 annually for three years, will allow Peoples to research the mechanism by which alcohol acts on one of its major target proteins in the central nervous system.
Peoples hopes that this project will give “a better understanding of how the alcohol molecule produces the effects on this protein and goes on to influence brain function” and that it will eventually “lead to better therapeutic agents for treating people with alcohol use disorders and alcoholism.”
His goal is to develop mutant receptor proteins as molecular tools. “We could introduce a mutant NMDA receptor that is alcohol insensitive into a brain cell or neuron and get a better idea how the protein is responsible for the effects of alcohol,” he said.
The Way Klingler Fellowships are awarded to full-time regular faculty at the associate or full professor rank who have potential for significant scholarship. One fellowship in science and one in humanities is awarded. The humanities fellow receives $20,000 annually for three years to fund critical research that requires time, access to information and travel.